Jennifer Lopez And Marc Anthony Split

Jenny's back on the singles block.

After seven years of marriage, Jennifer Lopez and Marc Anthony have separated, their rep tells Us Weekly exclusively.

PHOTOS: Jennifer and her adorable twins

"We have decided to end our marriage. This was a very difficult decision. We have come to amicable conclusion on all matters," they said in a statement. "It is a painful time for all involved, and we appreciate the respect of our privacy at this time."

The couple are parents to three-year-old twins Max and Emme.

Crooner Anthony, 42, was conspicuously absent at Saturday's star-packed BAFTA Brits to Watch bash in L.A., where wife Lopez, 40, met Prince William and Duchess Kate with mom Guadalupe as her date.