The risks go beyond grapefruit! Blood thinners and cholesterol lowering drugs can interact with these otherwise harmless foods.We’ve reported recently on the rising incidence of potentially dangerous drug interactions with grapefruit (and other citrus fruits such as Seville oranges and limes.) In fact, experts have warned that grapefruit juice can have serious interactions with more than 85 different drugs, and it can create an overdose effect if consumed by people using cholesterol lowering statins, antibiotics, calcium channel blockers and more.